Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?

J Med Chem. 2004 Apr 8;47(8):1869-78. doi: 10.1021/jm0305467.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkyl and Aryl Transferases / antagonists & inhibitors*
  • Alkyl and Aryl Transferases / chemistry
  • Animals
  • Antineoplastic Agents / chemical synthesis
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Clinical Trials as Topic
  • Drug Design
  • Farnesyltranstransferase
  • Genes, ras / drug effects
  • Humans
  • Neoplasms / drug therapy*

Substances

  • Antineoplastic Agents
  • Alkyl and Aryl Transferases
  • Farnesyltranstransferase